| POSITION TITLE |
Research Technician III |
| DEPARTMENT |
LTRI |
| EMPLOYMENT TYPE |
Regular Full Time |
| HOURS OF WORK |
37.5 hours per week |
| EMPLOYEE GROUP |
Non-Union |
| REPORTS TO |
Principal Investigator |
Organization Description:
The Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, a University of Toronto affiliated research centre, is one of the world's leading centres in biomedical research. With ground-breaking discoveries in research areas such as diabetes, genetic disorders, cancer and women’s and infants’ health, the Institute is committed to excellence in health research and the training of young investigators. Strong partnerships with the clinical programs of Mount Sinai Hospital ensure that scientific knowledge is used to promote human health. Your significant contributions will assist in maintaining our momentum in advancing our research.
Department Description:
Research in the lab is focused on understanding the biology of the glucagon-like peptides. Specific projects include physiological analyses of gut hormone action through studies of their respective receptors in preclinical studies.
Lab staff utilize a combination of techniques that involve cell culture, studies of signal, transduction, cell proliferation and apoptosis, with a major emphasis on generation and phenotypic analysis of mice with disruption of gut hormone action. The lab employs mouse models to delineate novel concepts of gut hormone action with potential therapeutic relevance.
Position Overview:
We are seeking a highly motivated Research Technician. The ideal candidate will also allocate 10% of their time for maintaining the smooth operation of the day-to-day lab operations
Responsibilities:
- The position involves research in mice, including genetically modified mouse lines, which require experience in breeding, weaning and genotyping
- Responsible for performing complex mouse phenotyping experiments, including biochemical, RNA, and histological analyses
- Ensure laboratory operations including procurement, installation and disposal of instrumentation, maintenance of equipment and instrumentation in working order, preventative maintenance, negotiation for quotes and service contract renewals
- Support the preparation of grant budgets
- Ensure compliance with all safety, technical and animal facility requirements that oversee research conduct in the lab
- Distribution and maintenance of relevant regulatory documents including protocol study manuals, SOPs and other study-specific tools and resources
- Assist in preparation of protocols for appropriate use of animals, chemical, reagents
- Supervise and delegate shared lab duties for the efficient operation of the lab
Qualifications:
- Bachelor's or Master's degree with 5 plus years of experience
- Experience with mouse metabolic phenotyping in mouse models of cardiometabolic and intestinal disease preferred
- Must have a practical understanding of molecular biology and whole animal physiology
- Candidate should have a strong record in and experience with mouse metabolic physiology, colony management and phenotyping
- The successful candidate must have excellent interpersonal, communication, organizational and record keeping skills
- Must be a team player
Please submit your resume and cover letter online.
We thank all candidates for applying. Only those short listed for an interview will be contacted.
In accordance with Institute’s policy and legislated health and safety requirements, employment is conditional upon the verification of credentials, completion of a health review, and demonstrating proof of immunity and vaccination status of vaccine-preventable diseases. All employees and affiliates will follow safe work practices and comply with health and safety policies, procedures, and training. Successful candidates will be required to provide two (2) written reference letters from their former employer(s)/supervisor(s).
We are a fully committed to fairness and equity in employment and our recruitment and selection practices. We encourage applications from Indigenous peoples, people with disabilities, members of sexual minority groups, members of racialized groups, women and any others who may contribute to the further diversification of our Sinai Health community. Accommodation will be provided in all parts of the hiring process as required under our Access for People with Disabilities policy. Applicants need to make their requirements known in advance.
The Lunenfeld-Tanenbaum Research Institute is a scent sensitive environment, and all members of the community are expected to refrain from wearing or using scented products while visiting or working at the Institute. We also support a barrier-free workplace supported by the Institute’s accessibility plan, accommodation and disability management policies and procedures. Should you require accommodation at any point during the recruitment process, including accessible job postings, please contact the Lunenfeld-Tanenbaum Human Resources Department.
| Posting open until April 20, 2025. We thank all candidates for applying. Only those selected for an interview will be contacted. |
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