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Sorry, the application deadline for this position was 10/15/2023

Reference Number: 000001860
Posted Date: 8/16/2023
Closing Date: 10/15/2023

Department: Lunenfeld Tanenbaum Research Institute
Position: Principal Investigator (2 positions)

POSITION TITLE  Principal Investigator (2 positions) 
EMPLOYMENT TYPE  Regular Full Time
HOURS OF WORK  37.5 hours per week 
REPORTS TO  Director , LTRI 



The Lunenfeld-Tanenbaum Research Institute of Sinai Health, a University of Toronto-affiliated biomedical research center, is recruiting emerging leaders in the area of Systems, Chemical, Developmental or Molecular Biology with a focus on studying and treating human diseases. The appointments will be for Principal Investigators (rank equivalent to Assistant Professor).

We seek applicants to develop innovative, outstanding and independent programs in Systems, Cellular, Chemical, Developmental or Molecular Biology.  Research approaches include, but are not limited to, the application of functional genomics, proteomics, metabolomics, chemical biology, single-cell analytics, structural biology and cell/tissue engineering to investigate biological processes or develop new therapeutic approaches using human and/or model organisms. Topic areas encompass network and systems biology, regenerative biology, immunology/microbiology, next-generation therapeutics, cellular physiology, and disease mechanisms. Applicants with combined computational and wet lab focus are also encouraged to apply.

The successful candidates will join the Lunenfeld-Tanenbaum Research Institute’s faculty, who are internationally renowned for their work in network biology, cancer, developmental and structural biology, imaging, and proteomics. With numerous discoveries in basic and applied research in cancer, stem cell biology, diabetes, genetic disorders, neurobiology and women’s and infants’ health, the Lunenfeld-Tanenbaum Research Institute is committed to excellence in health research and the training of young investigators. The Institute provides a research-intensive environment with modern and innovative core facilities that include proteomics, single-cell and spatial genomics platforms, robotics and imaging that drive technology development and are housed in the Network Biology Collaborative Centre. Sinai Health System is also the home of The Centre for Phenogenomics, a state-of-the-art facility for mouse models, and is a founding member of the Nanoscale Biomedical Imaging Facility. Close ties with flagship clinical programs focusing on fetal medicine and women’s health, cancer genetics, diabetes, autoimmune/inflammatory diseases and infectious disease, as well as a history of biotech entrepreneurship, ensure the successful application of our research findings. 

Lunenfeld-Tanenbaum Research Institute labs engage in productive collaborations within the Institute, Sinai Health System, the larger University of Toronto community, and beyond. The University of Toronto has one of the world's most concentrated and largest biomedical research communities, including 9 academic hospital research institutes that are fully affiliated with the University. Toronto is a vibrant, safe, multicultural city with excellent quality of life.


Investigators at the Lunenfeld-Tanenbaum Research Institute are appointed to independent positions equivalent to Assistant, Associate or Full Professor, depending on experience; preference for this opportunity will be given to individuals qualifying at the level of Assistant Professor. Investigators will be cross-appointed to appropriate research or clinical department(s) at the University of Toronto.

Successful candidates will hold a PhD and/or MD degree, with postdoctoral experience and an established record of research accomplishment as demonstrated by outstanding publications, presentations at international conferences, awards and accolades, and reference letters. The successful candidates will be expected to initiate and lead innovative, independent, and externally funded, research programs of the highest international calibre and impact.

We offer competitive and generous salaries and start-up packages commensurate with experience and qualifications.

The Lunenfeld-Tanenbaum Research Institute and Sinai Health are strongly committed to diversity within their community and especially welcome applications from racialized persons / persons of colour, women, Indigenous / Aboriginal People of North America, persons with disabilities, and members of sexual minority groups, and others who may contribute to the further diversification.

The Lunenfeld-Tanenbaum Research Institute and Sinai Health System recognize that scholars have varying career paths and that career interruptions due to personal circumstances can be part of an excellent academic record. Candidates are encouraged to explain any personal circumstances in order to allow for a fair assessment of their application. The committee will carefully consider any impact of career interruptions in their decision-making. 

As part of the University of Toronto and Sinai Heath System’s implementation of their Canada Research Chairs Equity, Diversity & Inclusion Action Plan, the successful candidate in this search MAY BE eligible for nomination for a CRC Tier 2 Chair if they self-identify as a member of the following federally designated groups, as defined by the Employment Equity Act (women, visible minorities, persons with disabilities, and Indigenous Peoples), or as trans, non-binary, or Two-Spirit. The nominee’s research area must align with the subject matter eligibility of CIHR.

Tier 2 Chairs are intended for exceptional emerging scholars. Nominees should be within ten years of receiving their PhD or MD degree (not including career breaks, such as maternity, parental or extended sick leave, clinical training, etc.). Applicants who are more than 10 years from having earned their highest degree (and where career breaks exist, such as maternity, parental or extended sick leave, clinical training, etc.) may have their eligibility for a Tier 2 chair assessed through the program’s Tier 2 justification process.

For further information on the federally endowed Canada Research Chairs Program, open to all nationalities, including eligibility criteria, please consult the Canada Research Chairs website. For more information about the CRC nomination process at the University of Toronto, contact Judith Chadwick, Assistant Vice-President, Research Services, at crc@utoronto.ca.

Application Instructions

Applications should include:

  1. A one-page structured summary that includes: A) a brief education/training history; B) a summary of the applicant’s most important research contributions (up to five), and C) an abstract of the research plan
  2. A cover letter
  3. A research statement highlighting the proposed research program (not exceeding 3 pages, including figures)
  4. A statement highlighting past and future commitment to EDI (0.5 to 1 page). Please  identify your strengths and experiences in increasing EDI in your previous institutional environments and in supporting diverse trainees and co-workers in the future.
  5. A complete curriculum vitae
  6. Three reference letters

Applications should be submitted via the Interfolio website prior to Oct 15th, 2023.  

Application link

Interfolio Faculty Search


Applicants needing additional information can contact Dr. Daniel Schramek at PI_search@lunenfeld.ca. E-mailed applications will not be accepted.


Application Process

This institution is using Interfolio's Faculty Search to conduct this search. Applicants to this position receive a free Dossier account and can send all application materials, including confidential letters of recommendation, free of charge.


Equal Employment Opportunity Statement


Sinai Health System recognizes that scholars have varying career paths and that career interruptions due to personal circumstances can be part of an excellent academic record. Candidates are encouraged to explain any personal circumstances in order to allow for a fair assessment of their application. Search committee members have been instructed to give careful consideration to, and be sensitive to the impact of, career interruptions in their assessments.

Sinai Health System is strongly committed to diversity within its community and especially welcomes applications from racialized persons / persons of colour, women, Indigenous / Aboriginal People of North America, persons with disabilities, and members of sexual minority groups, and others who may contribute to the further diversification of ideas.


As part of your application, you will be asked to complete a brief Diversity Survey directly on the Interfolio site. This form is voluntary and any information directly related to you is confidential and cannot be accessed by the search committee. Results will be aggregated for institutional planning purposes as part of Sinai Health System’s Equity, Diversity and Inclusion initiative.


In accordance with Institute’s policy and legislated health and safety requirements, employment is conditional upon the verification of credentials, completion of a health review, and demonstrating proof of immunity and vaccination status of vaccine-preventable diseases.

Sinai Health System is a scent-sensitive environment, and all members of the community are expected to refrain from wearing or using scented products while visiting or working at the Institute. We also support a barrier-free workplace supported by the Institute’s accessibility plan, accommodation and disability management policies and procedures. Should you require accommodation at any point during the recruitment process, including accessible job postings, please contact the Lunenfeld-Tanenbaum Human Resources Department via email at kdudas@lunenfeld.ca. All qualified applicants are strongly encouraged to apply; however, in accordance with Canadian immigration requirements, Canadians and permanent residents will be given priority.





Posting open until October 15, 2023 . We thank all candidates for applying. Only those selected for an interview will be contacted.

Hours: 37.5 hours per week

Contact Name: http://apply.interfolio.com/130205
Contact Email: http://apply.interfolio.com/130205
... applications accepted via external service.
Contact Phone: Online
Contact Fax: Online


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